Universität Wien

323115 VU NMR for Drug Design - MPS5 (2024S)

2.00 ECTS (1.00 SWS), SPL 32 - Pharmazie
Continuous assessment of course work
Moodle

Registration/Deregistration

Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).

Details

Language: English

Lecturers

Classes

15.04 09.00-11.00 2D313
16.04 09.00-11.00 2D313
17.04 09.00-11.00 2D313
18.04 09.00-11.00 2D313
19.04 09.00-11.00 2D313
22.04 09.00-11.00 2D313
23.04 09.00-11.00 2D313

Information

Aims, contents and method of the course

Protein-ligand interactions are at the heart of drug discovery research. NMR spectroscopy is perfectly suited to identify and validate protein-ligand interactions. A large number of NMR experiments are available. They are very powerful, but may also have pitfalls and limitations.
In this lecture, we will present central experiments for NMR in drug discovery, and assess their strengths and reliabilities.
Furthermore, methods for subsequent characterization of the interaction such as quantitative KD determination, binding mode analysis, or structure determination will be covered if time allows.

Assessment and permitted materials

Active cooperation

Minimum requirements and assessment criteria

Basic knowledge of NMR

Strongly recommend the lecture:
322052-1- Basics of NMR Spectroscopy - M14

Examination topics

Discussed scientific topics in the field of practical aspects of NMR for Drug Design in the form of short seminars.

Reading list

Association in the course directory

Last modified: Mo 15.04.2024 09:46