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330029 VO Nutrition and Gene Regulation (2016W)
Labels
LV für Masterstudierende- Voraussetzung: Zulasseung zum Masterstudium
Details
max. 40 participants
Language: German
Examination dates
- Friday 04.11.2016 10:15 - 11:45 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
- Friday 25.11.2016 10:15 - 11:45 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
- Friday 09.12.2016 09:45 - 11:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
Lecturers
Classes
LV-Termine:
Information
Aims, contents and method of the course
Assessment and permitted materials
Final written exam, 90 min, multiple choice, minimum requirements: 60%
Minimum requirements and assessment criteria
The students will understand
- the basic principles of gene regulation in humans,
- the role of transcription factors , their activation and regulation,
- the methods of nutrigenomics,
- how specific nutrients affect gene regulation and signal transduction as well as
- the specific transcription factors involved in these processes,
- the potential impact of these events on health and disease
- the basic principles of gene regulation in humans,
- the role of transcription factors , their activation and regulation,
- the methods of nutrigenomics,
- how specific nutrients affect gene regulation and signal transduction as well as
- the specific transcription factors involved in these processes,
- the potential impact of these events on health and disease
Examination topics
Lectures on the topics listed above, power point presentations, disscussion of pertinent literature
Reading list
Powerpoint-Präsentationen der Vorlesungen werden über Lernplattform zur Verfügung gestellt
Artikel/Übersichtsartikel zu aktuellen Themen der Nutrigenomik nach Ankündigung
Lehrbücher:
Regina Brigelius-Flohé, Hans-Georg Joost, Nutritional Genomics: Impact on Health and Disease: Nutrients, Genes and Genetic Variation in Health and Disease, Wiley-VCH Verlag GmbH & Co. KGaA; 1. Auflage 2006, ISBN-10: 3527312943
Yoshinori Mine, Kazuo Miyashita, Fereidoon Shahidi, Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions, John Wiley & Sons; 1. Auflage 2009, ISBN-10: 0813800331
Gerald H. Rimbach, Lester Packer, Jürgen Fuchs, Nutrigenomics (Oxidative Stress and Disease), Marcel Dekker Inc.; 1. Auflage 2005, ISBN-10: 0824726634
Martin Kohlmeier, Nutrigenetics: Applying the Science of Personal Nutrition, Elsevier Inc. 2013, First edition, ISBN: 978-0-12-385900-6 (http://ubdata.univie.ac.at/AC10817338 )
Artikel/Übersichtsartikel zu aktuellen Themen der Nutrigenomik nach Ankündigung
Lehrbücher:
Regina Brigelius-Flohé, Hans-Georg Joost, Nutritional Genomics: Impact on Health and Disease: Nutrients, Genes and Genetic Variation in Health and Disease, Wiley-VCH Verlag GmbH & Co. KGaA; 1. Auflage 2006, ISBN-10: 3527312943
Yoshinori Mine, Kazuo Miyashita, Fereidoon Shahidi, Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions, John Wiley & Sons; 1. Auflage 2009, ISBN-10: 0813800331
Gerald H. Rimbach, Lester Packer, Jürgen Fuchs, Nutrigenomics (Oxidative Stress and Disease), Marcel Dekker Inc.; 1. Auflage 2005, ISBN-10: 0824726634
Martin Kohlmeier, Nutrigenetics: Applying the Science of Personal Nutrition, Elsevier Inc. 2013, First edition, ISBN: 978-0-12-385900-6 (http://ubdata.univie.ac.at/AC10817338 )
Association in the course directory
Last modified: Sa 02.04.2022 00:27
- Transcriptional regulation
- Post-transcriptional regulation
- Modifications of chromatin structure
- DNA sequence elements with regulatory characteristics
Transcription factors:
- DNA-binding
- Mechanisms of action
- Regulating the regulators
Introduction into nutrigenomics:
- Definition
- Aims
- Methods:
-- Assessment ot transcription factors (e.g. ELISA, EMSA, supershift assays)
-- Transkriptomics (DNA microarray, RT-PCR)
Effects of macronutrients on gene expression:
- Effects of fatty acids on gene expression and corresponding transcription factors
- Effects of carbohydrates and insulin on gene expression and corresponding transcription factors
- Effects of amino acids on gene expression and corresponding transcription factors
Effects of micronutrients on gene expression:
- Retinol
- Cholecalciferol
- Iron
- Copper
- Zinc
- Secondary metabolites of plants (phytochemicals)
Nutrients and gene regulation from the perspective of nutritional scienes and nutritional medicine, e.g.:
- Nutrients, gene regulation and obesity
- Nutrients, gene regulation and metabolic syndrome
- Nutrients, gene regulation and atherosclerosis
Future aspects