330048 VO Organic chemistry (2016S)

Objectives
Part I:
Based on their knowledge already acquired in General and Inorganic Chemistry, the students will recognize the field of Organic Chemistry as area of carbon compounds. They will understand the correlation of functional groups and properties of substances, know about different forms of isomerism, be able to draw molecules using different forms of projection, get acquainted with important reactions in Organic Chemistry and be proficient in the most important reaction mechanisms.

Part II:
The students will be able to
classify natural product that are important for human nutrition and to discuss their mechanisms of action
understand actual as well as optional future values of natural products from a nutritional science perspective.

Contents
Part I:
- Basics of Organic Chemistry (chemistry of carbon, binding models, hybridisation);
- Acyclic und cyclic hydrocarbons, alkanes, alkenes, alkynes;
- Different ways of drawing chemical structures (Newman projection, Fischer projection);
- Basics of systematic nomenclature;
- Functional groups and properties of the corresponding chemical compounds
- Stereochemistry, isomerism, optical activity;
- Aromatic and heteroaromatic systems, heterocycles;
- Selected reactions in Organic Chemistry, introduction into the most important reaction mechanisms;
- Important basic building blocks in natural product chemistry: amino acids, sugars, nucleotides, fatty acids, lipids

Part II:
Definition of natural products chemistry
Distribution and structural variety of natural products
Basics of natural product synthesis
Possible uses and option values of natural products
Classification of natural products
Natural products with a carbon skeleton
Glykosides and glucosinolates
Isoprenoids: Terpenopids and steroids
Shikimi acid derivatives
Polyketides
Natural products with a nitrogen skeleton
Peptide toxins
Purine nucleotides
Alkaloids

Methods
Part I
Lectures on the topics listed above using overhead projection and - when indicated - blackboard, examples
Part II:
Lectures on the topics listed above, power point presentations, examples