442703 VO+UE Principles of RNA 3D Structure II (2014S)
Continuous assessment of course work
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Aims, contents and method of the course
The summer semester of this course will focus on: RNA 3D motifs and how to find additional instances of them in other RNA 3D structures, long-range interactions including pseudoknots, the geometry of RNA multi-helix junctions prediction of RNA secondary and 3D structure from sequence, probabilistic modeling of RNA sequence variability, visualization of RNA 3D structures, and other topics as time and interest allow.
Assessment and permitted materials
Long-term project, homework assignments, and exam.
Minimum requirements and assessment criteria
Acquire a solid working knowledge of basic RNA interactions including basepairs, stacking, and base-backbone interactions. Learn to search the RNA 3D structure database for RNA motifs of interest, both geometrically and symbolically. Develop abilities to predict aspects of RNA 3D structure from sequence, and to predict what sequences will be consistent with a given 3D structure.
Examination topics
Workshop interspersed with lectures.
Reading list
Association in the course directory
Last modified: Fr 31.08.2018 08:59