812316 VO Arzneistoffmetabolismus (2004S)
Arzneistoffmetabolismus: Grundlagen und klinische Anwendung
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Vorbesprechung am: Donnerstag, 4.3.2004
15.00 s.t. im Seminarraum 2D462
15.00 s.t. im Seminarraum 2D462
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N2270
Last modified: Fr 31.08.2018 09:01
Introduction to phase I and phase II metabolism; substrates, inducers, inhibitors of cytochrom P450, glucuronosyltransferases, sulfotransferases, acetyltransferases and glutathion-S-transferases; in vitro/in vivo methods of drug metabolism; pharmakogenetics, enzymkinetics (Km, Vmax, Ki); prediction of drug-drug interactions (examples from the Austria Codex - problem-based learning).