812378 SE Anleitung z. Diplomarbeit Pharmazeutische Chemie (2005S)

ECTS: 30.0
Objective: to take part at in-vitro research projects and to co-work in clinical pharma-cokinetic studies (design, performance, evaluation)
Content: By analysis of plasma and tissue samples of patients undergoing chemo-therapy, the fate of antineoplastic drugs (pharmacokinetics) and their metabolites can be determined. By this it is possible to: 1. establish individual dosage regimens, 2. introduce new polychemotherapeutic regimens, 3. verify drug interactions. Further, in-vitro experiments (human hepatocytes, cancer cell lines, enzyme reactions etc.) are performed to obtain more detailed information about metabolism of antineoplastic drugs.
Prerequisites: having passed all practical courses
Mode of examination: permanent