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300343 VO Genome structure and evolution (2017W)

2.00 ECTS (1.00 SWS), SPL 30 - Biologie


Language: English

Examination dates


Classes (iCal) - next class is marked with N

Vorbesprechung and first lecture: Thursday 05.10.2017, 11:00-13:00, ÜR3

Thursday 05.10. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 12.10. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 19.10. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 09.11. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 16.11. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 23.11. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG


Aims, contents and method of the course

This course offers an overview of plant genome structure and evolution. Plant genome structure (types of coding and non-coding DNA sequences that contribute to the genome function and evolution; mechanisms of their change) as well as main chromosomal landmarks (telomeres, centromeres, NORs) will be discussed. All these features will be compared with genomic features and evolutionary trends of other organisms (animals, including humans, insects etc.). The newest methods recently developed to analyze genome composition and function including methods to characterize the coding and repetitive DNA fractions (e.g., high-throughput sequencing) will also be introduced. The course will also introduce types and consequences of various genomic changes including polyploidy and more subtle chromosomal rearrangements as well as dynamics of mobile genetic elements in the genome, and discuss these in the comparative phylogenetic context. The course also offers a few hours of practical chromosome handling (microscopy): analyses of meiotic chromosome pairing and karyotypic landmarks (including localization of various types of DNA sequences in the chromosomes by FISH - demonstration).

Assessment and permitted materials

written exam (100%) from course material; Mindestanforderungen für positive Beurteilung: min. 50% of points

Minimum requirements and assessment criteria

To present and discuss in details the structure, types, and function of chromosomes, discuss genome structure and emphasize their role in evolutionary processes.
To introduce most important cytogenetic and genomic tools including state of the art next generation sequencing, and demonstrate how they can be used to infer genome evolution in comparative context in plants.

Examination topics


Reading list

Stebbins G.L. 1971. Chromosomal evolution in higher plants. Edward Arnold, London.
2. Fukui K. & Nakamya S. 1996. Plant chromosomes. Laboratory methods. CRC Press, Boca Raton.
3. Maluszynska J. (ed.) 1998. Plant cytogenetics. Silesian University Press, Katowice, Poland.
4. Schwarzacher T. & Heslop-Harrison P. 2000. Practical in situ hybridization. 2nd ed. BIOS, Oxford UK.
5. Levin D.A. 2002. The role of chromosomal change in plant evolution. Oxford University Press, New York, USA.
6. Singh R.J. 2003. Plant cytogenetics. CRC Press, Boca Raton.
7. Puertas M.J. & Naranjo T. (eds.) 2005. Plant cytogenetics. Karger, Basel.
8. Puertas M.J. & Naranjo T. (eds.) 2008. Reviews in plant cytogenetics. Karger, Basel.
9. Birchler J.A. & Pires J.C. (eds.) 2010. Advances in plant cytogenetics. Karger, Basel.
10. Plant Genome Diversity vol. 1 (2012) and 2 (2013). Springer

Association in the course directory

B-BAN 9, B-BMG 11, B-BMB 10, B-BOE 11, B-BZO 11, BBO 2, BAN 6, BMG 10, BMB 10, BOE 11, BPB 11, BZO 11, B-BPF 2, UF BU 10,

Last modified: Mo 07.09.2020 15:43