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300343 VO Genome structure and evolution (2018W)

2.00 ECTS (1.00 SWS), SPL 30 - Biologie

Registration/Deregistration

Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first serve).

Details

Language: English

Examination dates

Lecturers

Classes (iCal) - next class is marked with N

Vorbesprechung: 04.10.2018.
Lectures will be blocked: 2 hours per week (Thursdays 11:00-13:00) for six weeks. The course will finish with written exam.

Thursday 04.10. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 11.10. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 18.10. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 25.10. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 08.11. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 15.11. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 22.11. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG

Information

Aims, contents and method of the course

This course offers an overview of plant genome structure and evolution. Plant genome structure (types of coding and non-coding DNA sequences that contribute to the genome function and evolution; mechanisms of their change) as well as main chromosomal landmarks (telomeres, centromeres, NORs) will be discussed. All these features will be compared with genomic features and evolutionary trends of other organisms (animals, including humans, insects etc.). The newest methods recently developed to analyze genome composition and function including methods to characterize the coding and repetitive DNA fractions (e.g., high-throughput sequencing) will also be introduced. The course will also introduce types and consequences of various genomic changes including polyploidy and more subtle chromosomal rearrangements as well as dynamics of mobile genetic elements in the genome, and discuss these in the comparative phylogenetic context. The course also offers a few hours of practical chromosome handling (microscopy): analyses of meiotic chromosome pairing and karyotypic landmarks (including localization of various types of DNA sequences in the chromosomes by FISH - demonstration).

Assessment and permitted materials

written exam (100%) from course material; Positive evaluation: min. 50% of points

Minimum requirements and assessment criteria

To present and discuss in details the structure, types, and function of chromosomes, discuss genome structure and emphasize their role in evolutionary processes.
To introduce most important cytogenetic and genomic tools including state of the art next generation sequencing, and demonstrate how they can be used to infer genome evolution in comparative context in plants.

Examination topics

Lectures (material on moodle)

Reading list

Stebbins G.L. 1971. Chromosomal evolution in higher plants. Edward Arnold, London.
2. Fukui K. & Nakamya S. 1996. Plant chromosomes. Laboratory methods. CRC Press, Boca Raton.
3. Maluszynska J. (ed.) 1998. Plant cytogenetics. Silesian University Press, Katowice, Poland.
4. Schwarzacher T. & Heslop-Harrison P. 2000. Practical in situ hybridization. 2nd ed. BIOS, Oxford UK.
5. Levin D.A. 2002. The role of chromosomal change in plant evolution. Oxford University Press, New York, USA.
6. Singh R.J. 2003. Plant cytogenetics. CRC Press, Boca Raton.
7. Puertas M.J. & Naranjo T. (eds.) 2005. Plant cytogenetics. Karger, Basel.
8. Puertas M.J. & Naranjo T. (eds.) 2008. Reviews in plant cytogenetics. Karger, Basel.
9. Birchler J.A. & Pires J.C. (eds.) 2010. Advances in plant cytogenetics. Karger, Basel.
10. Plant Genome Diversity vol. 1 (2012) and 2 (2013). Springer

Association in the course directory

BBO 2, BAN 6, BMG 10, BMB 10, BOE 11, BPB 11, BZO 11, UF BU 10,

Last modified: Mo 07.09.2020 15:43