Universität Wien FIND

300343 VO Genome structure and evolution (2019W)

2.00 ECTS (1.00 SWS), SPL 30 - Biologie

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Details

Language: English

Examination dates

Lecturers

Classes (iCal) - next class is marked with N

Initial meeting AND FIRST LECTURE: 03.10.2019 11:00
Course will be blocked - every week two hours instead of one hour (last lecture on 14.11.2019).

Thursday 03.10. 11:00 - 12:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 10.10. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 17.10. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 24.10. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 31.10. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 07.11. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 14.11. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 28.11. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 05.12. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 16.01. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 23.01. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 30.01. 11:00 - 13:00 Übungsraum 3 (Fakultätszentrum für Biodiversität) Rennweg 1.OG

Information

Aims, contents and method of the course

This course offers an overview of plant genome structure and evolution. Plant genome structure (types of coding and non-coding DNA sequences that contribute to the genome function and evolution; mechanisms of their change) as well as main chromosomal landmarks (telomeres, centromeres, NORs) will be discussed. All these features will be compared with genomic features and evolutionary trends of other organisms (animals, including humans, insects etc.). The newest methods recently developed to analyze genome composition and function including methods to characterize the coding and repetitive DNA fractions (e.g., high-throughput sequencing) will also be introduced. The course will also introduce types and consequences of various genomic changes including polyploidy and more subtle chromosomal rearrangements as well as dynamics of mobile genetic elements in the genome, and discuss these in the comparative phylogenetic context. The course also offers a few hours of practical chromosome handling (microscopy): analyses of meiotic chromosome pairing and karyotypic landmarks (including localization of various types of DNA sequences in the chromosomes by FISH - demonstration).

Assessment and permitted materials

Written exam (100%) from course material; Positive evaluation: min. 50% of points

Minimum requirements and assessment criteria

Knowledge of the structure, types, and function of chromosomes; comparative genome structure and evolution; types and dynamics of repetitive DNAs in the genome; most important cytogenetic and genomic tools and how they contribute to our understanding of genome structure and evolution.

Examination topics

Lectures (material on moodle), recommended reading (optional)

Reading list

1. Stebbins G.L. 1971. Chromosomal evolution in higher plants. Edward Arnold, London.
2. Fukui K. & Nakamya S. 1996. Plant chromosomes. Laboratory methods. CRC Press, Boca Raton.
3. Maluszynska J. (ed.) 1998. Plant cytogenetics. Silesian University Press, Katowice, Poland.
4. Schwarzacher T. & Heslop-Harrison P. 2000. Practical in situ hybridization. 2nd ed. BIOS, Oxford UK.
5. Levin D.A. 2002. The role of chromosomal change in plant evolution. Oxford University Press, New York, USA.
6. Singh R.J. 2003. Plant cytogenetics. CRC Press, Boca Raton.
7. Puertas M.J. & Naranjo T. (eds.) 2005. Plant cytogenetics. Karger, Basel.
8. Puertas M.J. & Naranjo T. (eds.) 2008. Reviews in plant cytogenetics. Karger, Basel.
9. Birchler J.A. & Pires J.C. (eds.) 2010. Advances in plant cytogenetics. Karger, Basel.
10. Plant Genome Diversity vol. 1 (2012) and 2 (2013). Springer

Association in the course directory

BBO 2, BAN 6, BMG 10, BMB 10, BOE 11, BPB 11, BZO 11, UF BU 10,

Last modified: Th 28.11.2019 15:09